When numbers make health.

1. Social and health cost studies of a disease (quantification of consumed resources and determination of the costs of managing some types of patients, borne by the national health service and society as a whole)

2. Definition of the Value Dossier to negotiate price and reimbursement with national, regional and local health authorities

3. Preparation of cost studies for Quality Adjusted Life Years (QALYs), Cost Minimization Analysis (CMA), Cost Benefit Analysis (CBA), Cost Effectiveness Analysis (CEA), Cost Utility Analysis (CUA), Budget Impact Analysis (BIA)

4. Analysis, assessment and creation of clinical pathways on new or existing therapies and of diagnostic pathways for the treatment of certain diseases

5. Impact of the new drug on the diagnostic-therapeutic pathway for different disease as cardiovascular, gastroenterological, neurologic, infective, etc.

1. Economic models and disease modelling, created both with institutional, externally validated criteria, and as easy-to-use tools to support marketing, customized software and development of specific apps.

2. Customization and adaptation of models to specific national, regional and local contexts

3. Possibility to compare prices at a central and regional level and european level

4. Real-time update of cost, epidemiological and effectiveness data

5. Possibility to continuously update the results of budget-impact and cost-effectiveness models

6. Exclusive use of the disease modeling platform savedigital ® available to: decision-makers, physicians/clinicians interested in creating and updating databases in real time, payers, Market Access managers, pharmacoeconomic decision makers

SAVE carries out research activities in the field of Real World Data (RWD) and Real World Evidence (RWE), together with the University of Pavia, as founding partner of CEFAT, with reference to:

1. Governance systems and organizational tools for monitoring and evaluating the appropriateness of pharmaceutical and healthcare expenditure

2. Pharmacoeconomic analyses on data from Banca Dati Assistito (BDA) – Integrated Patients Database e Patients Registry

3. Support with Real World Data (RWD) for a national and regional planning and programming of pharmaceutical and health expenditure based on Real World Evidence (RWE)

4. Definition of specific indicators and permanent observers of populations and evaluation of the use of drugs and medical devices in terms of Outcomes Research

5. Statistical and economic analyses within research protocols, clinical databases and observational registries of patients

6. Complete economic evaluations: WTP Analysis, Cost Minimization Analysis (CMA), Cost Benefit Analysis (CBA), Cost Effectiveness Analysis (CEA), Cost Utility Analysis (CUA), Quality Adjusted Life Years (QALYs), Budget Impact Analysis (BIA)

7. Definition and planning of pharmacoeconomic research protocols and CRF planning

8. Applied research on social and health policies

1. Systematic literature reviews of outcomes research, pharmacoeconomics and HTA Heath Technology Assessment

2. Original research contributions, methodological essays in the field of HTA

3. Scientific posters and products for communication and presentation at dedicated workshops, medical congresses, international meetings

4. Participation in scientific workshops, symposia and congresses

5. Processing of clients’ proposals, work completion, and organization and control of the phases of submission and review of scientific work in the pharmacoeconomic field

6. Health Economics & Outcomes Research contents for institutional reports and supporting the marketing/sales process

S.A.V.E. carries out training and updating activities for professionals in the social-health and pharmaceutical sectors, as a natural carryover of its work in research and consulting. S.A.V.E. defines study seminars and workshops, and participates in congresses, in constant partnership with other national and international scientific bodies. The contents of the various subject areas are defined by constantly tackling the discussed themes in the S.A.V.E. research fields and considering suggestions from the social-health sector which are functional to Market Access activities. It is possible to request targeted programs for the in-depth analysis of specific interesting themes for a certain group of professionals, or choose the most functional plan in view of the nature of the program to be implemented (internal seminar, residential day of study, distance learning, workshop, frontal lectures).