S.A.V.E. Studi Analisi Valutazioni Economiche Srl is a research, consulting, and training company in Health Economics, Pharmacoeconomics, and Outcomes Research. It was founded in Milan in 1994, as a first crossroad between theoretical heritage, academic models, and business experience in Italy. S.A.V.E. offers multiple tools to support decision-making processes within Institutions and companies and for professionals in the healthcare and pharmaceutical sectors, aiming at exploiting resources more effectively.

S.A.V.E. is an accredited provider with QuESTIO, a system implemented by the Lombardia regional authority to recognize and assess research and technology transfer centers (CRTT, Centri di ricerca e trasferimento tecnologico). It is a member of ISPOR (International Society for Pharmacoeconomics and Outcomes Research). It is a partner of DOVE Medical Press, a medical scientific international publishing house exclusively issuing all S.A.V.E. papers on its indexed journals, with the possibility to buy reprints of the original articles.

S.A.V.E is the organizing secretariat of the Master course in pharmaceutical marketing (MAMAF) at the University of Pavia, Italy. It is also the editor of the journal Clinico Economics, and exclusively offers reprints and customized layouts of the published articles.

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S.A.V.E. is active in the fields of pharmacoeconomics, outcomes research and HTA, and offers tools to define, measure, and communicate the economic evidence of a product (drug and medical device) or treatment pathway. In that sense, academic research and consulting strategies work in synergy to offer an exhaustive and functional picture of the clients’ needs.

  • Pricing and Reimbursement

    1. Social and health cost studies of a disease (quantification of consumed resources and determination of the costs of managing some types of patients, borne by the national health service and society as a whole)

    2. Definition of the Value Dossier to negotiate price and reimbursement with national, regional and local health authorities

    3. Preparation of cost studies for Quality Adjusted Life Years (QALYs), Cost Minimization Analysis (CMA), Cost Benefit Analysis (CBA), Cost Effectiveness Analysis (CEA), Cost Utility Analysis (CUA), Budget Impact Analysis (BIA)

    4. Analysis, assessment and creation of clinical pathways on new or existing therapies and of diagnostic pathways for the treatment of certain diseases

    5. Impact of the new drug on the diagnostic-therapeutic pathway of a disease

  • Data Analysis

    1. Systematic reviews of literature in the HTA and pharmacoeconomics areas

    2. Pharmacoeconomic analyses on data from Banca Dati Assistito (BDA) – Integrated Patients Database e Patients Registry

    3. Statistical and economic analyses within research protocols, clinical databases and observational registries of patients

    4. Complete economic evaluations: WTP Analysis, Cost Minimization Analysis (CMA), Cost Benefit Analysis (CBA), Cost Effectiveness Analysis (CEA), Cost Utility Analysis (CUA), Quality Adjusted Life Years (QALYs), Budget Impact Analysis (BIA)

    5. Definition and planning of pharmacoeconomic research protocols and CRF planning

    6. Applied research on social and health policies

  • Scientific Publications

    1. Scientific papers and reviews of outcomes research

    2. Original research contributions, methodological essays in the field of HTA

    3. Scientific posters and products for communication and presentation at dedicated workshops, medical congresses, international meetings

    4. Participation in scientific workshops, symposia and congresses

    5. Processing of clients’ proposals, work completion, and organization and control of the phases of submission and review of scientific work in the pharmacoeconomic field

    6. Health Economics & Outcomes Research contents for institutional reports and supporting the marketing/sales process

  • Customized Models

    1. Economic models and disease modelling (created both with institutional, externally validated criteria, and as easy-to-use tools to support marketing – customized software and development of specific apps)

    2. Customization and adaptation of models to specific national, regional and local contexts

    3. Easily usable models all around Europe

    4. Possibility to compare prices at a central and regional level

    5. Model parameters can easily be modified after brand-name drugs become generics

    6. Real-time update of cost, epidemiological and effectiveness data

    7. Possibility to continuously update the results of budget-impact and cost-effectiveness models

    8. The savedigital platform is available to: decision-makers, physicians/clinicians interested in creating and updating databases in real time, payers, Market Access managers, pharmacoeconomic decision makers

  • Training

    S.A.V.E. carries out training and updating activities for professionals in the social-health and pharmaceutical sectors, as a natural carryover of its work in research and consulting. S.A.V.E. defines study seminars and workshops, and participates in congresses, in constant partnership with other national and international scientific bodies. The contents of the various subject areas are defined by constantly tackling the discussed themes in the S.A.V.E. research fields and considering suggestions from the social-health sector which are functional to Market Access activities. It is possible to request targeted programs for the in-depth analysis of specific interesting themes for a certain group of professionals, or choose the most functional plan in view of the nature of the program to be implemented (internal seminar, residential day of study, distance learning, workshop, frontal lectures).

Clinico Economics

Italian Articles on Outcomes Research

Clinico Economics is a peer-reviewed pharmacoeconomics and outcomes research journal on the economic and health-policy consequences of medical devices and pharmacological strategies.

University partners: Università degli Studi di Pavia

Master in Pharmaceutical Marketing MAMAF


At S.A.V.E., the staff is composed of a strong group of researchers and professionals who are hands-on in the medical, pharmaceutical, economic and statistical fields, as well as in social-health policies and risk management. All partners and members of the scientific ethic committee are actively involved in academia and have an ongoing scientific relationship with their university departments and institutes. S.A.V.E. also cooperates with a large network of external consultants, built up in 20 years of activity through synergies developed with academia, institutions, clinicians, and research organizations, at a national and international level. S.A.V.E. scientific director is Prof. Giorgio L. Colombo.
Speaker 1
Giorgio L.
Scientific Director
& Founder
Speaker 3
Di Matteo
Senior Statistician Manager
& Senior Associate Consultant
Speaker 5
Giacomo M.
Strategic Project Manager & Associate Consultant
Speaker 6
Administrative Services
Speaker 4
M. Chiara
HEOR Analyst
Speaker 6
HEOR Analyst
Speaker 6
Junior HEOR Analyst
Speaker 6
Statistician Consultant
  • Pharmaceutical companies

    Abiogen Pharma
    Allergan Pharmaceutilcas
    Argon Healthcare Italia
    Astellas Pharma
    Berna Biotech
    Biogen – Dompè
    Bracco Injeneering
    B.R.A.H.M.S. Italia
    Bristol-Mayers Squibb
    Bruno Farmaceutici
    CD pharma group
    Chiesi Farmaceutici
    DOC Generici
    Dr. Schär
    GE Healthcare
    Gilead Sciences
    Hill+Knowlton strategies Italy
    IMS Health information solution Italy
    Johnson & Johnson Medical
    LEO Pharma
    McCann Complete Medical
    Meda Pharma
    MSD Italia
    Lundbeck Italia
    Menarini Ricerche
    Merck Serono
    MSD Italia
    Mundipharma Pharmaceuticals
    Novartis Farma
    Otsuka Pharmaceutical Italy
    Pierre Fabre Pharma
    Procter & Gamble
    Sankyo Pharma Italia
    Sanofi Pasteur MSD
    Schering Plough
    Swiss Medical Care
    Takeda Italia
    Takeda Pharmaceuticals
    Teva Italia
    Therabel GiEnne Pharma
    UCB Pharma
    Zambon Italia
  • Institutions

    Public and Academic Institutions
    Accademia Nazionale di Medicina
    Assobiomedica Servizi
    Ass. Lombarda Titolari di Farmacia
    Centro Studi e Ricerche sulla Famiglia, Milano
    Ist. Malattie Infettive e Medicina Pubblica
    Éupolis Lombardia
    Réseau Européen des Instituts de la Famille
    Università Cattolica del Sacro Cuore, Milano
    Università degli Studi di Pavia
    Regione Lombardia
    ISS Istituto Superiore di Sanità
    Ministero della Salute

    No Profit Organizations
    ASBI, Associazione Italiana Spina Bifida
    Aragorn, iniziative per il no-profit
    Rotary Club Bollate Nirone
    WalterVinci Onlus
    MAGIS ITALIA - Gesuiti Missionari Italiani
    Hospitals And Clinical Organizations
    AIOM - Associazione Italiana di Oncologia Medica
    Azienda Ospedaliera G. Salvini, Garbagnate Milanese
    Azienda Ospedaliera di Busto Arsizio, Varese
    Azienda Ospedaliera Niguarda Ca’ Granda
    Ospedale Caduti Bollatesi
    Clinica Morgagni, Catania
    Noi Medici
    SIMG Palermo

    Other Organizations
    Ager, Associazione per la ricerca geriatrica e lo studio della longevità
    Business International
    Dove Medical Press
    Fondazione Leonardo, Milano
    Infor scuola
    Ismu, Iniziative e studi sulla multietnicità


Via G. Previati 74, 20149 Milano | Tel. +39 02.48519230 | Fax +39 02.73960369 | Email info@savestudi.it
P.IVA / C.F. e n. d’iscrizione Registro Imprese Milano 11327060155