S.A.V.E. Studi Analisi Valutazioni Economiche Srl is a research, consulting, and training company in Health Economics, Pharmacoeconomics, and Outcomes Research. It was founded in Milan in 1994, as a first crossroad between theoretical heritage, academic models, and business experience in Italy. S.A.V.E. offers multiple tools to support decision-making processes within Institutions and companies and for professionals in the healthcare and pharmaceutical sectors, aiming at exploiting resources more effectively.

S.A.V.E. Studi research center is a founding partner, together with the University of Pavia, of CEFAT Center of Pharmaceuticals Economics and Medical Technologies Evaluation which carries out research in the field of Real World Data (RWD) and Real World Evidence (RWE) and their applications to the pharmaceutical market, medical devices and life sciences industries.

In collaboration with University of Pavia - Department of Drugs Science, S.A.V.E organize and support the postgraduate Master (MAMAF) on Marketing management in the pharmaceutical industry.

S.A.V.E official journal is ClinicoEconomics - Italian Articles on Outcomes Research Journal, and in collaboration with Making Life Srl offers reprints and customized layouts of the published articles.

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S.A.V.E. is active in the fields of pharmacoeconomics, outcomes research and HTA, and offers tools to define, measure, and communicate the economic evidence of a product (drug and medical device) or treatment pathway. In that sense, academic research and consulting strategies work in synergy to offer an exhaustive and functional picture of the clients’ needs.

  • Pricing and Reimbursement

    1. Social and health cost studies of a disease (quantification of consumed resources and determination of the costs of managing some types of patients, borne by the national health service and society as a whole)

    2. Definition of the Value Dossier to negotiate price and reimbursement with national, regional and local health authorities

    3. Preparation of cost studies for Quality Adjusted Life Years (QALYs), Cost Minimization Analysis (CMA), Cost Benefit Analysis (CBA), Cost Effectiveness Analysis (CEA), Cost Utility Analysis (CUA), Budget Impact Analysis (BIA)

    4. Analysis, assessment and creation of clinical pathways on new or existing therapies and of diagnostic pathways for the treatment of certain diseases

    5. Impact of the new drug on the diagnostic-therapeutic pathway for different disease as cardiovascular, gastroenterological, neurologic, infective, etc.

  • Customized Models

    1. Economic models and disease modelling, created both with institutional, externally validated criteria, and as easy-to-use tools to support marketing, customized software and development of specific apps.

    2. Customization and adaptation of models to specific national, regional and local contexts

    3. Possibility to compare prices at a central and regional level and european level

    4. Real-time update of cost, epidemiological and effectiveness data

    5. Possibility to continuously update the results of budget-impact and cost-effectiveness models

    6. Exclusive use of the disease modeling platform savedigital ® available to: decision-makers, physicians/clinicians interested in creating and updating databases in real time, payers, Market Access managers, pharmacoeconomic decision makers

  • Data Analysis

      SAVE carries out research activities in the field of Real World Data (RWD) and Real World Evidence (RWE), together with the University of Pavia, as founding partner of CEFAT, with reference to:

    1. Governance systems and organizational tools for monitoring and evaluating the appropriateness of pharmaceutical and healthcare expenditure

    2. Pharmacoeconomic analyses on data from Banca Dati Assistito (BDA) – Integrated Patients Database e Patients Registry

    3. Support with Real World Data (RWD) for a national and regional planning and programming of pharmaceutical and health expenditure based on Real World Evidence (RWE)

    4. Definition of specific indicators and permanent observers of populations and evaluation of the use of drugs and medical devices in terms of Outcomes Research

    5. Statistical and economic analyses within research protocols, clinical databases and observational registries of patients

    6. Complete economic evaluations: WTP Analysis, Cost Minimization Analysis (CMA), Cost Benefit Analysis (CBA), Cost Effectiveness Analysis (CEA), Cost Utility Analysis (CUA), Quality Adjusted Life Years (QALYs), Budget Impact Analysis (BIA)

    7. Definition and planning of pharmacoeconomic research protocols and CRF planning

    8. Applied research on social and health policies

  • Scientific Publications

    1. Systematic literature reviews of outcomes research, pharmacoeconomics and HTA Heath Technology Assessment

    2. Original research contributions, methodological essays in the field of HTA

    3. Scientific posters and products for communication and presentation at dedicated workshops, medical congresses, international meetings

    4. Participation in scientific workshops, symposia and congresses

    5. Processing of clients’ proposals, work completion, and organization and control of the phases of submission and review of scientific work in the pharmacoeconomic field

    6. Health Economics & Outcomes Research contents for institutional reports and supporting the marketing/sales process

  • Training

    S.A.V.E. carries out training and updating activities for professionals in the social-health and pharmaceutical sectors, as a natural carryover of its work in research and consulting. S.A.V.E. defines study seminars and workshops, and participates in congresses, in constant partnership with other national and international scientific bodies. The contents of the various subject areas are defined by constantly tackling the discussed themes in the S.A.V.E. research fields and considering suggestions from the social-health sector which are functional to Market Access activities. It is possible to request targeted programs for the in-depth analysis of specific interesting themes for a certain group of professionals, or choose the most functional plan in view of the nature of the program to be implemented (internal seminar, residential day of study, distance learning, workshop, frontal lectures).

Clinico Economics

Italian Articles on Outcomes Research

Clinico Economics is a peer-reviewed pharmacoeconomics and outcomes research journal on the economic and health-policy consequences of medical devices and pharmacological strategies.

University partners: Università degli Studi di Pavia

  • Center of Pharmaceuticals Economics and Medical Technologies Evaluation

  • Postgraduate Master on Marketing management in the pharmaceutical industry MAMAF

  • Team

    At S.A.V.E., the staff is composed of a strong group of researchers and professionals who are hands-on in the medical, pharmaceutical, economic and statistical fields, as well as in social-health policies and risk management. All partners and members of the scientific ethic committee are actively involved in academia and have an ongoing scientific relationship with their university departments and institutes. S.A.V.E. also cooperates with a large network of external consultants, built up in 20 years of activity through synergies developed with academia, institutions, clinicians, and research organizations, at a national and international level. S.A.V.E. scientific director is Prof. Giorgio L. Colombo.
    Speaker 1
    Giorgio L.
    Scientific Director
    & Founder
    Speaker 3
    Di Matteo
    Senior Statistician Manager
    & Senior Associate
    Speaker 5
    Giacomo M.
    Senior Strategic Project Manager
    & Senior Associate
    Speaker 4
    M. Chiara
    Senior HEOR analyst
    Speaker 6
    Senior HEOR Analyst Manager
    Speaker 6
    HEOR Analyst
    Speaker 6
    Statistician Consultant
    Speaker 6
    Speaker 6
    • Pharmaceutical companies

      Abiogen Pharma
      Allergan Pharmaceutilcas
      Argon Healthcare Italia
      Astellas Pharma
      Berna Biotech
      Biogen – Dompè
      Bracco Injeneering
      B.R.A.H.M.S. Italia
      Bristol-Mayers Squibb
      Bruno Farmaceutici
      CD pharma group
      Chiesi Farmaceutici
      DOC Generici
      Dr. Schär
      GE Healthcare
      Gilead Sciences
      Hill+Knowlton strategies Italy
      IMS Health information solution Italy
      Johnson & Johnson Medical
      LEO Pharma
      McCann Complete Medical
      Meda Pharma
      MSD Italia
      Lundbeck Italia
      Menarini Ricerche
      Merck Serono
      MSD Italia
      Mundipharma Pharmaceuticals
      Novartis Farma
      Otsuka Pharmaceutical Italy
      Pierre Fabre Pharma
      Procter & Gamble
      Sankyo Pharma Italia
      Sanofi Pasteur MSD
      Schering Plough
      Swiss Medical Care
      Takeda Italia
      Takeda Pharmaceuticals
      Teva Italia
      Therabel GiEnne Pharma
      UCB Pharma
      Zambon Italia
    • Institutions

      Public and Academic Institutions
      Accademia Nazionale di Medicina
      Assobiomedica Servizi
      Ass. Lombarda Titolari di Farmacia
      Centro Studi e Ricerche sulla Famiglia, Milano
      Ist. Malattie Infettive e Medicina Pubblica
      Éupolis Lombardia
      Réseau Européen des Instituts de la Famille
      Università Cattolica del Sacro Cuore, Milano
      Università degli Studi di Pavia
      Regione Lombardia
      ISS Istituto Superiore di Sanità
      Ministero della Salute

      No Profit Organizations
      ASBI, Associazione Italiana Spina Bifida
      Aragorn, iniziative per il no-profit
      Rotary Club Bollate Nirone
      WalterVinci Onlus
      MAGIS ITALIA - Gesuiti Missionari Italiani
      Hospitals And Clinical Organizations
      AIOM - Associazione Italiana di Oncologia Medica
      Azienda Ospedaliera G. Salvini, Garbagnate Milanese
      Azienda Ospedaliera di Busto Arsizio, Varese
      Azienda Ospedaliera Niguarda Ca’ Granda
      Ospedale Caduti Bollatesi
      Clinica Morgagni, Catania
      Noi Medici
      SIMG Palermo

      Other Organizations
      Ager, Associazione per la ricerca geriatrica e lo studio della longevità
      Business International
      Dove Medical Press
      Fondazione Leonardo, Milano
      Infor scuola
      Ismu, Iniziative e studi sulla multietnicità


    Via G. Previati 74, 20149 Milano | Tel. +39 02.48519230 | Fax +39 02.73960369 | Email info@savestudi.it
    Cap. Soc. € 30.000,00 i. v. | REA 1454903 | P.IVA / C.F. e n. d’iscrizione Registro Imprese Milano 11327060155